df = pd.read_excel("filename.xlsx", header = None)

# 獲取列數
rows = df.shape[0]

# 獲取儲存格內容
df.iat[1, 0]

# 修改儲存格內容
df.iloc[1, 0] = "test"
# 但修改後必須要儲存才會修正檔案內容
# df.to_excel('test_result.xlsx', sheet_name = 'sheet1')

import pandas as pd

# Create a Pandas dataframe from some data.
df = pd.DataFrame({'Data': [10, 20, 30, 20, 15, 30, 45]})

# Create a Pandas Excel writer using XlsxWriter as the engine.
writer = pd.ExcelWriter('pandas_simple.xlsx', engine='xlsxwriter')

# Convert the dataframe to an XlsxWriter Excel object.
df.to_excel(writer, sheet_name='Sheet1')

# Close the Pandas Excel writer and output the Excel file.
writer.save()